TopCrate is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more ›

TRENDING ON AMAZON

Listerine Cool Mint Antiseptic Mouthwash (33.8 fl oz / 1L) Review: Is It Worth It?

The ADA-accepted essential-oil antiseptic mouthwash — four active essential oils that kill 99.9% of the germs that cause bad breath, plaque and gingivitis, in the iconic Cool Mint flavor.

★★★★½4.8/5Based on hundreds of thousands of Amazon reviewsADA-accepted, 99.9% germ kill

Quick answer: Yes — Listerine Cool Mint is worth being the mouthwash step in your daily routine. ADA-accepted with a Seal of Acceptance based on clinical trials, four essential oils that kill 99.9% of the germs causing bad breath and plaque, 52% more plaque reduction and 21% more gingivitis reduction than brushing and flossing alone, and the classic Cool Mint flavor that keeps the burn tolerable. Alcohol-based — switch to Listerine Zero if you have dry mouth or alcohol sensitivity, and pair with a fluoride toothpaste since Cool Mint doesn't contain fluoride. Not going to whiten your teeth on its own. But as the twice-daily antiseptic bookend to brushing and flossing, this is the mouthwash the dental community has been endorsing for 145 years for a reason.

Listerine Cool Mint Antiseptic Mouthwash (33.8 fl oz / 1L)

Product image from the Amazon listing.

9.8
OUT OF 10

Our verdict

Yes — Listerine Cool Mint is worth being the mouthwash step in your daily routine. ADA-accepted with a Seal of Acceptance based on clinical trials, four essential oils that kill 99.9% of the germs causing bad breath and plaque, 52% more plaque reduction and 21% more gingivitis reduction than brushing and flossing alone, and the classic Cool Mint flavor that keeps the burn tolerable. Alcohol-based — switch to Listerine Zero if you have dry mouth or alcohol sensitivity, and pair with a fluoride toothpaste since Cool Mint doesn't contain fluoride. Not going to whiten your teeth on its own. But as the twice-daily antiseptic bookend to brushing and flossing, this is the mouthwash the dental community has been endorsing for 145 years for a reason.

The short version

Listerine Cool Mint is the mouthwash equivalent of what CeraVe is to face wash — the drugstore staple your dentist actually recommends, still made with the same four essential oils (eucalyptol, menthol, methyl salicylate, thymol) it launched with in 1879. In the modern era it's earned the American Dental Association's Seal of Acceptance and clinical evidence showing it reduces plaque 52% more and gingivitis 21% more than brushing and flossing alone. The Cool Mint version tames the classic 'Listerine burn' just enough to make a 30-second rinse tolerable without losing the germ-killing efficacy. It's not sexy, it's not new, and it's not going to whiten your teeth on its own — but as the twice-a-day bookend to brushing and flossing, this is the mouthwash the dental community has been endorsing for decades.

Pros & cons

Pros

  • ADA-accepted (Seal of Acceptance) for reducing plaque and gingivitis
  • Four essential oils kill 99.9% of germs that cause bad breath
  • Reduces plaque 52% more than brushing and flossing alone
  • Reduces gingivitis 21% more than brushing and flossing alone
  • Cool Mint flavor tames the classic Listerine burn
  • Massive 1L (33.8 fl oz) bottle lasts weeks of twice-daily use

Cons

  • Contains alcohol — those with dry mouth or alcohol sensitivity should try Zero
  • The burn is still real for first-time users
  • Won't whiten teeth on its own — pair with whitening toothpaste or strips

Why people love it

1

Measure 20 mL

Pour 20 mL (about 4 teaspoons, or to the fill line on the cap) into the dosing cup. Full-strength — do not dilute.

2

Swish for 30 seconds

Swish vigorously between teeth and around gums for 30 seconds. Don't cut it short — the essential oils need the full 30 seconds to penetrate biofilm and kill the target germs.

3

Spit and don't rinse

Spit out completely. Don't rinse with water afterward and don't eat or drink for 30 minutes — that lets the antimicrobial effect keep working on residual germs.

Who it's for

  • Anyone with bad breath, morning breath or lingering food/coffee/onion odors
  • People with early gingivitis or bleeding gums
  • Adults maintaining oral health between dental cleanings
  • Households looking for one ADA-accepted mouthwash the whole family can share (adults; not for children under 12)

Why Listerine Cool Mint is still the dentist-recommended mouthwash after 145 years

Listerine has one of the longest continuous product histories in drugstore health care — the original formula launched in 1879, and while packaging and flavors have evolved, the active essential-oil chemistry has stayed remarkably consistent. That's not brand nostalgia; it's because the four essential oils (eucalyptol, menthol, methyl salicylate, thymol) actually work at killing the specific bacteria responsible for plaque, gingivitis and volatile-sulfur-compound-caused bad breath, and better alternatives haven't materialized in almost a century and a half of oral-hygiene R&D. Chlorhexidine is stronger but stains teeth and is prescription-only. CPC is comparable and alcohol-free but has slightly less anti-plaque evidence. Essential oils remain the drugstore antiseptic that clinical evidence keeps validating.

The ADA Seal of Acceptance for reducing plaque and gingivitis is the credential that matters most. The ADA doesn't hand out its seal easily — manufacturers submit clinical trial data that the ADA independently evaluates, and only formulations with proven efficacy get the seal. Listerine Cool Mint has had it for decades and continues to earn it. The published clinical evidence is the source of the '52% more plaque reduction' and '21% more gingivitis reduction' claims on the bottle — those aren't marketing numbers, they're from randomized controlled trials comparing brushing/flossing alone vs brushing/flossing plus twice-daily Listerine. In an oral care category flooded with products making unverified '99% germ kill' claims, Listerine Cool Mint is the one where the clinical evidence actually holds up.

Listerine Cool Mint vs alcohol-free options — when to switch to Zero or Total Care

The alcohol in classic Listerine Cool Mint serves a real purpose (it helps solubilize the essential oils into the water base), but it's also the source of both the burn and the concerns some people have about dry mouth. For most healthy adults, the alcohol is fine at the concentrations used and the twice-daily 30-second exposure isn't a problem. But there are specific cases where alcohol-free Listerine Zero is genuinely a better fit: (1) chronic dry mouth (xerostomia), which can be caused by medications, aging, or medical conditions — alcohol worsens dry mouth. (2) People in recovery from alcohol addiction, where any exposure is off-limits. (3) People who genuinely can't tolerate the burn even at 30 seconds — the burn compliance issue is real and if it makes you rinse for 10 seconds instead of the required 30, you're not getting the benefit. (4) Children over 6 (though most pediatric dentists prefer a fluoride rinse over antiseptic for this age).

Listerine Total Care is a different upgrade — it adds fluoride to the essential-oil base, which turns the mouthwash step into both an antiseptic rinse AND a cavity-prevention step. Best for adults with a cavity-prone history or an orthodontic history. If you're already using a fluoride toothpaste like Sensodyne Repair & Protect or Crest Pro-Health, Cool Mint is enough. If you want an extra fluoride hit, Total Care. And for maximum whitening add-on results, pair the Listerine rinse with Crest 3D Whitestrips applied per the strip's schedule — the two products don't interact, and using them together on the same day is fine.

How to build the maximum-benefit oral care routine around Listerine

The dentist-endorsed order for maximum benefit: (1) floss first, before anything else — use string floss or Plackers Micro Mint floss picks between every tooth. Flossing lifts food and biofilm out of tight spaces so the following steps can actually reach the tooth surfaces. (2) Brush thoroughly for 2 minutes with a fluoride toothpaste like Sensodyne Repair & Protect or Crest 3D White. A good electric toothbrush like the Philips Sonicare 4100 or Oral-B Pro makes 2 minutes actually effective. (3) Spit but don't rinse — leave the fluoride on your teeth. (4) Rinse with 20 mL Listerine Cool Mint for the full 30 seconds. (5) Spit but don't rinse. (6) Don't eat or drink for 30 minutes. Repeat morning and night.

Additional tools that raise the whole routine's effectiveness: a water flosser like a Waterpik once daily for people with tight teeth or gum pockets that string floss can't reach — the pulsing water dislodges biofilm string floss misses. Whitening products like whitestrips run in parallel — they don't replace the routine, they work on top of it. Tongue scraping (a cheap plastic or metal scraper) removes the biofilm on the tongue that many mouthwashes and toothpastes can't reach — a big contributor to bad breath that a lot of people miss. And a dental cleaning every 6 months no matter how good your home routine is — the professional scaling reaches biofilm below the gumline that no home tool can. Listerine Cool Mint is the mouthwash piece of a routine, not a replacement for the routine — do all the parts and the whole thing works.

See Listerine Cool Mint on Amazon

Check the latest price, photos and buyer reviews on Amazon.

Check Price on Amazon →Sold and shipped by Amazon

Frequently asked questions

Does Listerine Cool Mint actually work?

Yes — with real clinical evidence backing every claim on the bottle. Listerine is ADA-accepted (the American Dental Association Seal of Acceptance, awarded only after clinical trials verify the manufacturer's claims), and multiple published studies show that using Listerine twice daily reduces plaque 52% more and gingivitis 21% more than brushing and flossing alone. The active mechanism is four essential oils (eucalyptol, menthol, methyl salicylate, thymol) that penetrate the biofilm bacteria live in and kill 99.9% of the germs that cause bad breath, plaque and gingivitis. It's genuinely one of the few drugstore products with a Seal of Acceptance that reflects real clinical evidence rather than marketing.

Listerine Cool Mint vs Listerine Total Care vs Listerine Zero — which should I buy?

Different jobs. Cool Mint is the original antiseptic — best for germ-killing and bad breath, contains alcohol, ADA-accepted for reducing plaque and gingivitis. Total Care adds fluoride to the essential-oil base — best if you want cavity prevention rolled into your mouthwash step, ADA-accepted for cavity prevention plus antiseptic action. Listerine Zero uses the same essential oils but without alcohol — best for people with dry mouth, alcohol sensitivity, or those who find the original burn too intense (also better if you dislike the taste). If you're a first-time buyer picking one, Cool Mint is the classic. If you want fluoride in your mouthwash, Total Care. If you can't tolerate the burn or want alcohol-free, Zero.

How long should I swish Listerine Cool Mint?

30 seconds, full strength, undiluted — no more, no less. The 30-second window is what the ADA and Listerine's own clinical trials use, and cutting it to 15 seconds significantly reduces the antimicrobial effect (the essential oils need time to penetrate the biofilm bacteria live in). Longer than 30 seconds doesn't add meaningful benefit and just increases the intensity of the burn. Use 20 mL (about 4 teaspoons) — that's the fill line on the dosing cap. Don't dilute with water — the essential oil concentrations are tuned for the full-strength solution.

Should I rinse with water after using Listerine?

No — spit out the mouthwash and skip the water rinse. The residual antimicrobial effect keeps working on biofilm bacteria for a while after you spit, and rinsing with water washes away the essential oils that are doing the work. Same rule applies after brushing with fluoride toothpaste — spit, don't rinse — so fluoride stays on the teeth. If you want the maximum benefit: floss first (or use Plackers floss picks), brush with a fluoride toothpaste like Sensodyne Repair & Protect, spit without rinsing, then rinse with Listerine, spit without rinsing. Don't eat or drink for 30 minutes.

Is Listerine safe to use daily, and can it damage tooth enamel?

Yes to daily use, no to enamel damage. Listerine Cool Mint has a mildly acidic pH but not aggressively so, and it doesn't erode enamel with normal twice-daily use — this is a common concern that turns out to be unfounded when you look at the actual pH (around 4.2, above the enamel dissolution threshold) and the short exposure time (30 seconds). Dentists routinely recommend twice-daily use as part of a normal oral care routine. The one caveat: don't brush immediately after using acidic mouthwash — the mild acidity can temporarily soften enamel, and brushing during that window is what damages it. Wait 20-30 minutes between mouthwash and brushing, or (better) rinse AFTER brushing, not before.

Listerine Cool Mint vs Crest Pro-Health, Colgate Total, and TheraBreath — which mouthwash is best?

Each covers a different priority. Listerine Cool Mint (essential oils, alcohol) is best for maximum germ-killing and plaque/gingivitis reduction — the ADA-accepted essential-oil formula has more clinical evidence than any competitor. Crest Pro-Health (cetylpyridinium chloride, alcohol-free) is best for people who want strong antiseptic action without the burn — CPC is another proven antimicrobial. Colgate Total (also CPC-based) is a similar alcohol-free option — pairs well with Colgate Total whitening toothpaste for a matching-brand routine. TheraBreath (alcohol-free, focuses on volatile sulfur compounds) is best specifically for chronic bad breath from sulfur-producing bacteria — different mechanism than antiseptic mouthwashes. If you're not sure which to pick, Listerine Cool Mint is the safest default because of the ADA Seal and the largest clinical evidence base.

As an Amazon Associate, TopCrate earns from qualifying purchases at no extra cost to you. Listerine is a cosmetic oral care product, not a medical treatment. Not for children under 12. Product image, price, availability and ratings are shown on Amazon and are subject to change.

Listerine Cool MintView on Amazon →